The model examines how aerosols are deposited on the inner walls of the respiratory tract and helps in the treatment process of persons suffering from respiratory tract diseases using inhaled aerosols.
The model is intended to create as realistic a simulation as possible of a part of human respiratory tract (from the throat to 7 generations). It comprises the branching internal cavity with the inlet hole for aerosol entry and a set of outlet holes for aerosol exit.
The model consists of a set of dismountable interconnected parts which together demarcate the branched internal cavity. Some parts are made of partially transparent or translucent material, which is advantageous for visually monitoring the course of aerosol deposition.
In experimental research, use of this new model may help acquire unique knowledge of the transport and deposition of particles in the particular lung segments.
Another advantage is the opportunity to study flow characteristics during the breathing cycle – flows through individual branches, pressure loss both in single tubes and the model as a whole.
The newly developed model has great potential for use in various fields of application, particularly in the healthcare industry, pharmaceutical industry and education. Thanks to the Technology Transfer Office it is protected as a patent.
Let us find out some more about one of the inventors:
JAN JEDELSKÝ is a respected Czech expert in experimental fluid mechanics. Since 1999, he has been working at the Faculty of Mechanical Engineering at the Brno University of Technology as a college lecturer in the Department of Thermodynamics and Environmental Engineering at the Energy Institute. He is an author of a range of scientific articles in both Czech and international scientific journals. He is participating in a range of scientific projects and is successfully working with prestigious Czech associations.
His scientific and research activity is focused on studying flow in single- or multi-phase systems using optical measuring methods; in particular, he is examining the transport and deposition of particles in the human respiratory tract, researching and developing atomizing nozzles, and studying air flow from ventilating equipment. As part of his work on aerosol transport, he is engaged in long-term cooperation with U.S. research centres.
Main photo: Leslie Samuel. Interactive-biology.com